Regenerative Medicine: Natural & Effective alternative for chronic pain.

A Natural Solution

Prolotherapy & Orthobiologic approaches such as PRP with concentrated mesenchymal stem cells are cutting-edge approaches in the field of Regenerative Medicine. Current evidence suggests that steroid shots should not be the gold standard of treatment for musculoskeletal pain and that regenerative injections along with therapeutic exercises may form the best strategy to treat chronic joint pain in non-surgical patients.

Proloterapy: Tissue Regeneration

Prolotherapy (short for proliferative therapy) helps repair your connective tissue by encouraging new, healthy, extra-cellular matrix to form. This significantly strengthens ligaments & tendons by correcting the laxity in those tissues. Prolotherapy begins by naturally stimulating the healing process and increasing circulation. Then, the microdose of stem cells and collagen stimulates the body to start building its own collagen matrix to regenerate and repair tissue. Prolotherapy solutions contain dextrose along with botanical ingredients such as arnica for pain & micro-dose of stem cells and collagen (porcine origin) manufactured under strict international ISO 13485 certification for medical devices.
Platelet Rich Plasma (PRP)

Platelet-rich plasma (PRP) has been a breakthrough in the stimulation and acceleration of bone and soft tissue healing. It represents a cutting-edge orthobiologics approach that utilizes a centrifuged sample of your own blood. PRP contains powerful mesenchymal stem cells & growth factors to help regenerate tissue and treat pain. Research shows that PRP performs better than steroid shots at 6 and 12 month follow-ups.
Prolotherapy With Ozone

Ozone stimulates fibroblastic activity which results in the initiation of the repair process by stimulating collagen deposition. Despite its strong oxidative quality, when delivered in low therapeutic concentrations, ozone quickly reacts with tissues as an immunomodulator, an inducer of endothelial nitric oxide, a paradoxical inducer of antioxidant enzymes and a recruiter of stem cells.

Why Regenerative Medicine?

Increase Strength & Function

As inflammation decreases, function and strength of the injured tissue is restored. Treatments also induce collagen fiber production which strengthens connective tissue such as ligaments and tendons. As tendons and ligaments strengthen and “tighten” up, the clicking, locking and popping of joints resolves. As the cell metabolism in the injured tissue improves, the patient is able to progress strengthening and stabilization exercises.
Relieve Pain & Regenerate Tissue

Botanical ingredients such as arnica have analgesic effects by halting pro-inflamatory mediators and interrupting the cycle of chronic pain. Ozone also has an effect on the inflammatory cascade by altering the breakdown of arachidonic acid to inflammatory prostaglandins, this in turn reduces pain.
PRP contains various growth factors and cytokines such as platelet-derived growth factors (PDGF-aa, PDGF-bb, PDGF-ab), TGF-β (TGF-b1, TGF-b2), fibroblast growth factor (FGF), insulin-like growth factors 1 and 2 (IGF-1 and IGF-2, respectively), vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), which all assist with regenerating tissue.
Alternative To Steroid Injections

Acute injury results in signals to the body to begin the healing process. During this process, the body removes damaged tissue and replaces it with new, healthy tissue, creating an inflammatory state that can be painful. Anti-inflammatories or steroids treat the pain of inflammation but also suppress the healing process. Steroid injections are now known to increase tissue breakdown (catabolism), leading to more pain down the road. Prolotherapy & PRP however, seek to replicate the normal, tissue-healing process by interrupting the cycle of chronic pain & stimulating your body’s natural ability to heal

What sets us apart?

Not All PRP is Created Equal! Platelet counts matter.
Platelet rich plasma is a complex composition of cellular components. A single injection of properly-prepared PRP can heal a host of injuries. Multiple scientific studies done by Marx, Giusti, Kevy and others provide proof of bone and soft tissue healing with a minimum PRP platelet count of 1,000,000 platelets per microliter. This translates to a minimum of 1 billion platelets per milliliter. We utilize the best kits available to ensure adequate and consistent concentration of platelets for successful PRP administration.
Ultrasound Guided Muskuloskeletal Injections are key to effective treatment.
Ultrasound-guided MSK injections allow the practitioner to visualize the needle in real-time as it enters the body and traverses to the desired location. This assures that the injection accurately targets the intended site for maximum therapeutic benefit and minimal pain.
Staying abreast of the best practices in Regenerative Medicine.
In order to offer the best in-office regenerative medicine procedures to his patients, Dr. Ramburn has studied with pioneer physicians in the field of orthobiologics including PRP & stem cells. He has also sought out world leaders in diagnostic & interventional ultrasonography in the UK & the US.

Who we treat

Seniors with osteoarthritis

A growing body of evidence supports the use of PRP for joint degeneration, especially knee osteoarthritis. PRP performs better than hyaluronic acid or steroid injections.
Patients with chronic migraine

Tension headaches and migraines can occur as a result of instability & inflammation in the cervical spine. Prolotherapy can strengthen and heal the laxity in cervical vertebral ligaments to eliminate chronic, decade-long migraines.
Weekend Warriors

Orthobiologics used to be reserved for professional athletes who wanted to extend their careers but now offers an effective solution to recreational athletes who keep pushing the limits of physical performance.
Athletes with sports injuries

Young athletes can benefit from both PRP & prolotherapy to delay surgery during the competitive season or avoid surgery altogether.
Tendinopathy conditions

Tendon tissue can heal more rapidly with Prolotherapy & PRP, allowing patients to avoid surgery altogether.
Patients with meniscus injury

Patients with meniscus tears can remain active but are at much higher risk of developing joint osteoarthritis at a younger age. PRP can offer a long-term protective and strengthening effect.
Patients with plantar fasciitis

Plantar Fasciitis can be a debilitating condition that can be quickly resolved with acupuncture alone or in combination with PRP. This avoids much more invasive surgery or steroid injections.